Results from over half of all conducted randomized controlled trials (RCTs), especially those with negative or unfavorable results, never get published. This means, searching only electronic databases that index published literature does not provide the entire spectrum of information; additionally, a bias is induced, since most trials having negative results get omitted. This is extremely […]
Systematic reviews (SRs) face a major challenge while identifying all the relevant research, including randomised controlled trials (RCTs) irrespective of their publication status.(1) Unpublished, selectively reported, or non-reported research can lead to poorer quality clinical trials, thus leading to suboptimal care delivery. It also overlooks the opportunities for potential scientific progress.(2) Such incomplete publication status […]
